Increasing evidence suggests that imbalanced gut microbiota may play a role in insulin resistance in Type 2 Diabetes patients and exercise has shown to have positive effects on the gut microbiome and metabolism.

Several studies over the past decade have associated the gut microbiome and metabolic disorders such as obesity and type 2 diabetes (T2D), yet the exact mechanisms are not fully understood.

The commensal bacterium Akkermansia muciniphila has garnered considerable attention for its association with leanness as well as for its other health benefits in relation to obesity, excess weight and type 2 diabetes.

The gut microbiota is now believed to be a factor involved in the onset of cardiometabolic disorders such as obesity. In human and rat studies, the commensal* bacterium Akkermansia muciniphila– which is naturally present in large quantities in the gut microbiota of healthy people – has been gaining a lot of attention for its association with leanness and for producing several health benefits against obesity and type 2 diabetes.